Mucinous Adenocarcinoma Arising from Chronic Fistula-In-Ano: A Case Report
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Abstract
Mucinous adenocarcinoma of the fistula tract is a rare consequence of fistula-in-ano accounted
for approximately 2-3% of perianal cancers. Due to its rarity, no specific guidelines are available
on diagnostic modality and treatment of choice. Early diagnosis carries a good prognosis, but
most of the time, patients are presented with advanced stages of disease. Chronic and recurrent
perianal fistula and abscess often mask the malignant transformation, especially when the index
of suspicion is low. Diagnosis is ascertained by tissue biopsy and supported by imaging modality
such as MRI. Oncological resection with neoadjuvant or adjuvant radiotherapy and systemic
therapy is proven to have a benefit in a patient’s overall survival. This article reports a case of
mucinous adenocarcinoma of the fistula tract in a 61-year-old gentleman who had a previous
history of recurrent unresolved perianal sepsis and fistula.
Keywords: Perianal fistula, anorectal adenocarcinoma, fistula-in-ano.
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