A Pragmatic Study Of Porcine Acellular Dermal Matrix Mesh In Ventral And Parastomal Hernia Repairs. Evaluation Of Outcomes From A Tertiary Centre.

Main Article Content

S Daniel
M Solkar
R Sehgal
K Riyad

Abstract

Aims and Objectives: Incidence of complex ventral hernias and those with contamination are increasing. Synthetic meshes are not favoured due to increased risk of wound complications. Biologic meshes are used as an alternative given their biocompatible safety, but, there is lack of strong evidence to recommend its routine use. Hence, it is up to institutions to evaluate the safety and efficacy to support its continuing usage, which is the basis of this study.


 


Methods: A retrospective review of a prospectively maintained PADM mesh database was performed focussing on midline and parastomal hernias. Demographic data, surgical techniques and short- and long-term complications were reviewed.


 


Results: 71cases, (acute/elective 10/61) were included. The median age group, sex ratio in the acute and elective groups were 67 years (36-83yrs) and 62years (25-93yrs), 2:1 and 4:3 respectively. Mean ASA score was 3.4 in acute and 2.4 in elective group.  Midline hernias constituted 37/ 61 (60%) and Parastomal hernias, 40% (24/61). Component separation was performed in 29 cases, which includes bilateral anterior component separation in 16, unilateral anterior component in 11 and posterior component separation in 2. Median length of stay was 11days (1-180d) and 15 days (1-159d) in the elective and acute groups respectively. Median length of follow up was 18 months (12 -72 months). There were 5 deaths within 90 days.  Recurrences were noted in 6/37 (16%) midline repairs and 8/24 (33%) parastomal hernias.


Conclusion: Our limited PADM series showed acceptable results in comparison with available studies. As such we find it a useful adjunct in the repair of complex ventral hernias.


 

Downloads

Download data is not yet available.

Article Details

How to Cite
Daniel, S., Solkar, M., Sehgal, R., & Riyad, K. (2023). A Pragmatic Study Of Porcine Acellular Dermal Matrix Mesh In Ventral And Parastomal Hernia Repairs. Evaluation Of Outcomes From A Tertiary Centre. British Journal Of Surgical Science, 4(1). https://doi.org/10.54323/bjoss.2024.32
Section
GENERAL SURGERY

References

Hodgkinson J, Worley G, Warusavitarne J, Hanna G, Vaizey C, Faiz O. Evaluation of the

Ventral Hernia Working Group classification for long-term outcome using English Hospital

Episode Statistics: a population study. Hernia. 2021;25:977-84.

Sandvall BK, Suver DW, Said HK, Mathes DW, Neligan PC, Dellinger EP, et al. Comparison of

synthetic and biologic mesh in ventral hernia repair using components separation technique.

Annals of Plastic Surgery. 2016;76(6):674-9.

Rosen MJ, Krpata DM, Petro CC, Carbonell A, Warren J, Poulose BK, et al. Biologic vs

synthetic mesh for single-stage repair of contaminated ventral hernias: a randomized clinical

trial. JAMA surgery. 2022;157(4):293-301.

Breuing K, Butler CE, Ferzoco S, Franz M, Hultman CS, Kilbridge JF, et al. Incisional ventral

hernias: review of the literature and recommendations regarding the grading and technique

of repair. Surgery. 2010;148(3):544-58.

Hufford T, Tremblay JF, Sheikh MTM, Marecik S, Park J, Zamfirova I, et al. Local parastomal

hernia repair with biological mesh is safe and effective. The American Journal of Surgery.

;215(1):88-90.

Slater N, Montgomery A, Berrevoet F, Carbonell A, Chang A, Franklin M, et al. Criteria for

definition of a complex abdominal wall hernia. Hernia. 2014;18:7-17.

Kanters AE, Krpata DM, Blatnik JA, Novitsky YM, Rosen MJ. Modified hernia grading scale

to stratify surgical site occurrence after open ventral hernia repairs. Journal of the American

College of Surgeons. 2012;215(6):787-93.

Passot G, Villeneuve L, Sabbagh C, Renard Y, Regimbeau JM, Verhaeghe P, et al. Definition of

giant ventral hernias: development of standardization through a practice survey. International

journal of surgery. 2016;28:136-40.

Muysoms F, Campanelli G, Champault G, DeBeaux A, Dietz U, Jeekel J, et al. EuraHS: the

development of an international online platform for registration and outcome measurement

of ventral abdominal wall hernia repair. Hernia. 2012;16:239-50.

Flum DR, Horvath K, Koepsell T. Have outcomes of incisional hernia repair improved with

time?: A population-based analysis. Annals of surgery. 2003;237(1):129.

Luijendijk RW, Hop WC, Van Den Tol MP, De Lange DC, Braaksma MM, IJzermans JN, et al.

A comparison of suture repair with mesh repair for incisional hernia. New England Journal

of Medicine. 2000;343(6):392-8.

Ko JH, Wang EC, Salvay DM, Paul BC, Dumanian GA. Abdominal wall reconstruction:

lessons learned from 200 “components separation” procedures. Archives of surgery.

;144(11):1047-55.

Wegdam J, Thoolen J, Nienhuijs S, De Bouvy N, de Vries Reilingh T. Systematic review of

transversus abdominis release in complex abdominal wall reconstruction. Hernia. 2019;23:5-

Sbitany H, Kwon E, Chern H, Finlayson E, Varma MG, Hansen SL. Outcomes analysis of

biologic mesh use for abdominal wall reconstruction in clean-contaminated and contaminated

ventral hernia repair. Annals of plastic surgery. 2015;75(2):201-4.

Limura E, Giordano P. Biological implant for complex abdominal wall reconstruction: a single

institution experience and review of literature. World Journal of Surgery. 2017;41:2492-501.

Richmond B, Ubert A, Judhan R, King J, Harrah T, Dyer B, et al. Component separation

with porcine acellular dermal reinforcement is superior to traditional bridged mesh repairs

in the open repair of significant midline ventral hernia defects. The American Surgeon.

;80(8):725-31.

Clemens MW, Selber JC, Liu J, Adelman DM, Baumann DP, Garvey PB, et al. Bovine versus

porcine acellular dermal matrix for complex abdominal wall reconstruction. Plastic and

reconstructive surgery. 2013;131(1):71-9.

Morales-Conde S, Hernández-Granados P, Tallón-Aguilar L, Verdaguer-Tremolosa M, López-

Cano M. Ventral hernia repair in high-risk patients and contaminated fields using a single

mesh: proportional meta-analysis. Hernia. 2022;26(6):1459-71.